Data for: Dataset for: Lymphatic Pumping Technique Alters Whole Blood Parameters and Metastatic Melanoma in an Age-Dependent Manner
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This dataset contains the minimal source data underlying all figures and analyses for the manuscript “Lymphatic Pumping Technique Alters Whole Blood Parameters and Metastatic Melanoma in an Age-Dependent Manner.” The study examines whether therapeutic touch applied in the setting of metastatic disease influences tumor burden, immune response, and hematologic parameters across the lifespan using a mouse model of experimental melanoma metastasis. Included files comprise quantitative source data for all graphs and statistical analyses, in vivo and ex vivo IVIS images of metastatic burden, hematologic values, animal IDs, treatment group assignments, timepoints, and western blot densiometry, and the source files for all of the figures. Primary imaging evidence is also provided, including unedited in vivo and ex vivo IVIS images and uncropped western blot files corresponding to the figures in the manuscript. Data are organized in the order of the figures in the publication, allowing readers to directly map each file to its associated result. Together, these materials enable independent reanalysis of tumor growth, metastatic spread, immunotherapy response, and age-dependent hematologic effects of Lymphatic Pumping Technique (LPT).
本数据集包含论文《淋巴泵动技术(Lymphatic Pumping Technique, LPT)以年龄依赖方式改变全血参数与转移性黑色素瘤》中所有图表与分析所依托的最小化原始数据。本研究采用实验性黑色素瘤转移小鼠模型,探究转移性疾病背景下实施的治疗性触摸是否会在整个生命周期内影响肿瘤负荷、免疫应答与血液学参数。所包含的文件涵盖所有图表与统计分析的定量原始数据、反映肿瘤负荷的体内(in vivo)与体外(ex vivo)IVIS(活体成像系统)图像、血液学指标、实验动物编号、治疗组分配方案、时间节点以及蛋白质印迹光密度数据,同时包含所有图表的原始文件。本数据集还提供了核心成像证据,包括与论文图表对应的未编辑体内、体外IVIS图像,以及未裁剪的蛋白质印迹原始文件。数据按照论文中图表的顺序进行编排,便于读者直接将每份文件与其对应的研究结果相对应。上述所有材料可支持研究人员独立重复分析淋巴泵动技术(LPT)在肿瘤生长、转移扩散、免疫治疗应答以及年龄依赖型血液学影响方面的相关效应。



