SH1404683.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE 为界定、识别、交流以及处理基于DNA的物种假说（Species Hypotheses，SH）提供了统一的标准化路径。国际核酸序列数据库中的所有真菌内转录间隔区（Internal Transcribed Spacer，ITS）序列，通过应用一套动态距离阈值（0.5%~3.0%）被聚类至近似物种级别的聚类单元。所有物种假说均会被赋予一个以数字对象标识符（DOI）为形式的唯一且稳定的标识名称，其分类学与生态学注释信息均通过分布式网络第三方注释工作完成核验。系统会综合该物种假说内所有序列的鉴定结果，尽可能为其匹配对应的分类单元名称及其所属的分类阶元（如门、纲、目等）。研究人员会选取一条经自动或人工指定的代表序列，用以指代每个物种假说。上述代表序列已通过（https://unite.ut.ee/repository.php）向全球科研群体公开，可用于本地序列相似性检索、高通量测序分析流程等各类研究场景。随着公共真菌ITS序列数据量的持续增长，该系统与配套数据集将自动进行更新。