Frequency of HIV-1 drug-resistance mutations in ART-experienced and -naïve adult patients (≧15 years old) (<i>n</i> = 90)^a.

ART, antiretroviral therapy; NNRTI, non-nucleoside reverse-transcriptase inhibitor; NRTI, nucleoside reverse-transcriptase inhibitor; PI, protease inhibitor; and TAMs, thymidine analog-associated mutations. aHIV-1 drug-resistance mutations were detected according to the latest definition of the International AIDS Society-USA panel [10]. For ART-naïve patients, transmitted drug resistance was defined according to the latest definition of the WHO drug-resistance surveillance [11].抗反转录病毒治疗（antiretroviral therapy, ART）、非核苷类反转录酶抑制剂（non-nucleoside reverse-transcriptase inhibitor, NNRTI）、核苷类反转录酶抑制剂（nucleoside reverse-transcriptase inhibitor, NRTI）、蛋白酶抑制剂（protease inhibitor, PI）及胸苷类似物相关突变（thymidine analog-associated mutations, TAMs）。 HIV-1药物耐药突变的检测参照美国国际艾滋病学会专家组[10]的最新定义。对于抗反转录病毒治疗初治患者，传播性药物耐药的定义参照世界卫生组织（WHO）最新的药物耐药监测标准[11]。