RI Tomogram datasets
收藏资源简介：
This dataset contains results presented in the following manuscript: Kim and Guck, 'The relative densities of cell cytoplasm, nucleoplasm, and nucleoli are robustly conserved during cell cycle and drug perturbations,' available on bioRxiv (https://doi.org/10.1101/2020.04.14.040774) and includes two comma separated text files ('*.txt') containing analysis data from optical diffraction tomography. The text files includes <br>1. Cell Type (HeLa FUCCI or RPE FUCCI)2. Treatment (control, cytoD, nocodazole, TSA, and anacardic acid)3. Cell cycle (G1, Early S, G2)4-7. Mean RI of cytoplasm, nucleoplasm, perinuclear cytoplasm, and nucleoli of individual cell8-9. Dry mass and volume of nucleoplasm10-11. Dry mass and volume of cytoplasm12-13. Dry mass and volume of nucleolus14-15. Sphericity of cell and nucleus (Fig4_5_HeLa_Conditions.txt only)
本数据集包含Kim与Guck发表于bioRxiv预印本平台的研究手稿《细胞周期与药物扰动下细胞胞质、核质及核仁的相对密度均高度保守》的相关结果，手稿链接为：https://doi.org/10.1101/2020.04.14.040774。数据集包含两份逗号分隔的文本文件（*.txt），存储了光学衍射层析成像的分析数据，各文件包含以下字段： 1. 细胞类型：HeLa FUCCI或RPE FUCCI 2. 处理方式：对照组、细胞松弛素D（cytoD）、诺考达唑（nocodazole）、曲古抑菌素A（TSA）、腰果酸 3. 细胞周期时相：G1期、早期S期、G2期 4-7. 单个细胞的胞质、核质、核周胞质及核仁的平均折射率（Refractive Index, RI） 8-9. 核质的干质量与体积 10-11. 胞质的干质量与体积 12-13. 核仁的干质量与体积 14-15. 细胞与细胞核的球形度（仅存在于Fig4_5_HeLa_Conditions.txt文件中）
