Isoniazid Preventive Therapy (IPT) uptake and Tuberculin Skin Test (TST) uptake among adults receiving primary HIV care in South Africa .

We aimed to evaluate Isoniazid Preventive Therapy (IPT) and tuberculin skin testing (TST) uptake under primary care clinic conditions, and determine health care worker (HCW) fidelity to the 2014 South African IPT guidelines. Following training on IPT guidelines and tuberculin skin testing (TST), 3 primary care clinics identified their IPT implementation strategy in a participatory manner. Using routine register data, TST uptake was determined 3 months before and 5 months after the intervention. Records were reviewed to identify IPT/TST uptake and factors associated with IPT initiation among adults living with HIV.

本研究旨在评估基层医疗诊所环境下的异烟肼预防性治疗（Isoniazid Preventive Therapy, IPT）与结核菌素皮肤试验（tuberculin skin testing, TST）的开展情况，并明确医护人员（health care worker, HCW）对2014年南非异烟肼预防性治疗指南的执行依从性。研究人员在完成异烟肼预防性治疗指南与结核菌素皮肤试验相关培训后，3家基层医疗诊所以参与式方式确定了各自的异烟肼预防性治疗实施策略。本研究利用常规医疗登记数据，分别统计了干预前3个月与干预后5个月的结核菌素皮肤试验开展率；同时通过回顾病历记录，明确了异烟肼预防性治疗/结核菌素皮肤试验的开展情况，以及艾滋病病毒感染者成人启动异烟肼预防性治疗的相关影响因素。