Compounds that inhibit SFV replication in the SFV-Rluc screening assay.
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aIC50 values for SFV replication were determined using SFV-Rluc infection (MOI 0.001 in BHK cells and detection at 14 h post-infection).bCell viability IC50 values were determined by ATP assay after 48 h exposure of BHK cells.cSelectivity indices (SI) were calculated as the ratio of the two values. All results represent the mean values of two individual experiments both run in triplicate (CV ranged from 8.1 to 21.3% in the SFV-Rluc experiments). NC = natural compounds, PC = pharmaceutical compounds.
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2015-12-02



