Electroencephalogram dynamics during unconsciousness mediated by GABAergic-anesthetics

This dataset of electroencephalogram (EEG) activity was collected from subjects undergoing general anesthesia using GABAergic agents. The typical EEG of subjects during unconsciousness mediated by GABAergic anesthetics shows slow-delta oscillations (0.3 - 4Hz) and alpha oscillations (8 – 14Hz). At higher doses, these oscillations devolve into burst suppression, a state of profound brain inactivation. This data was used to investigate the transition between these states of unconsciousness. It was collected as part of a larger study to investigate the changes in brain activity during unconsciousness mediated by GABAergic anesthetics. All data collection and experimental protocols were approved by the Mass General Brigham Human Research Committee.

本数据集记录了使用GABAergic类药物进行全身麻醉的受试者脑电图（EEG）活动。在由GABAergic麻醉剂介导的无意识状态下，受试者的典型EEG表现为慢波δ节律（0.3 - 4Hz）和α节律（8 - 14Hz）。在高剂量下，这些节律逐渐演变为爆发抑制，这是一种深度的脑部失活状态。本研究数据被用于探究这些无意识状态之间的转变。这些数据是作为一项更大规模研究的一部分被收集的，旨在研究由GABAergic麻醉剂介导的无意识状态下脑活动的变化。所有数据收集和实验方案均经Mass General Brigham人类研究委员会批准。