Association of known IBD SNPs.

“Previously reported SNPs” are those IBD snps added to the design of the ImmunoChip; one per locus is shown here. Since 2 phenotypes were tested for this table (CD and UC) and 100 of the SNPs were not in linkage disequilibrium in Puerto Rico controls, the Bonferroni correction for multiple comparisons is 0.05/(2*100) = 0.00025.Association of known IBD SNPs.既往报道的单核苷酸多态性（Single Nucleotide Polymorphism，SNP）指纳入免疫芯片（ImmunoChip）设计的炎症性肠病（Inflammatory Bowel Disease，IBD）相关单核苷酸多态性位点，本研究中每个基因座仅展示一个位点。由于本表格针对克罗恩病（Crohn’s Disease，CD）与溃疡性结肠炎（Ulcerative Colitis，UC）两种表型开展检验，且波多黎各对照样本中有100个单核苷酸多态性位点未处于连锁不平衡（linkage disequilibrium）状态，因此多重比较的邦费罗尼校正（Bonferroni correction）阈值为0.05/(2×100)=0.00025。已知炎症性肠病相关单核苷酸多态性位点的关联分析。