Descriptive statistics.

Background
Diabetes Mellitus is a prevalent disease with a growing impact on individuals worldwide. Evaluating the prevalence of subclinical left ventricular dysfunction and understanding its associations with microvascular complications, uncontrolled glycemia, diabetes duration, and patient age is crucial. Our aim is to determine the utility of screening for this condition.
Methods
We conducted a retrospective cohort study involving 159 asymptomatic individuals with type 2 diabetes. Bivariate analysis was employed to assess potential factors and their associations with subclinical left ventricular dysfunction. Patients with a history of cardiac disease or interventions were excluded.
Results
The average age of our sample was 61.5 years. Almost half of the patients exhibited an HbA1c exceeding 7% (50.3%), and approximately half had an ejection fraction (EF) of less than 55% (50.9%). In the bivariate analysis, a notable difference in microvascular diabetic complications was observed among different EF groups. Specifically, nephropathy (62%), neuropathy (57.5%), and retinopathy (74.4%) were significantly more prevalent among patients with an EF < 55%. We also identified a significant age difference between groups, with a higher mean diabetes duration (14.1 ± 7.7 years) in the lower EF group. Notably, 63.7% of patients with an HbA1c exceeding 7% exhibited an EF < 55%. Older patients were associated with a lower EF, with an adjusted odds ratio (aOR) of 0.94. An HbA1c of 7% or less was linked to a higher likelihood of an EF > 55%.
Conclusion
We established a correlation between subclinical left ventricular systolic dysfunction and microvascular complications. However, further extensive prospective research is necessary to deepen our understanding of these associations and their clinical implications.

背景：糖尿病（Diabetes Mellitus）是一种全球范围内患病率日益攀升、对个体健康影响持续扩大的常见疾病。评估亚临床左心室功能障碍（subclinical left ventricular dysfunction）的患病率，并明确其与微血管并发症、血糖控制不佳、糖尿病病程以及患者年龄之间的关联，具有至关重要的临床意义。本研究旨在明确该病症筛查的应用价值。
方法：本研究开展了一项回顾性队列研究（retrospective cohort study），纳入159名无症状2型糖尿病患者。研究采用双变量分析（bivariate analysis），评估潜在影响因素与亚临床左心室功能障碍之间的关联。排除存在心脏病史或接受过心脏介入治疗的患者。
结果：本研究样本的平均年龄为61.5岁。近半数患者的糖化血红蛋白（HbA1c）水平超过7%（占比50.3%），约半数患者的射血分数（ejection fraction, EF）低于55%（占比50.9%）。双变量分析结果显示，不同射血分数分组的糖尿病微血管并发症存在显著差异。具体而言，射血分数<55%的患者中，糖尿病肾病（nephropathy，62%）、糖尿病神经病变（neuropathy，57.5%）以及糖尿病视网膜病变（retinopathy，74.4%）的患病率均显著更高。本研究还发现两组患者的年龄存在显著差异，射血分数较低组的平均糖尿病病程更长（14.1±7.7年）。值得注意的是，糖化血红蛋白水平超过7%的患者中，有63.7%表现为射血分数<55%。老年患者与较低的射血分数相关，校正比值比（adjusted odds ratio, aOR）为0.94。糖化血红蛋白水平≤7%的患者，其射血分数>55%的可能性更高。
结论：本研究证实了亚临床左心室收缩功能障碍与微血管并发症之间存在相关性。然而，仍需开展大规模的前瞻性研究，以进一步深化对这些关联及其临床意义的认识。