1st C+S-DG

C + S: Context + Shock. Young male C57BL/6J mice were exposed to a contextual fear conditioning paradigm that consisted of: Placement into a novel spatial context for 2 min. After 2 min, a 1 sec (0.5 mA) shock was administered through a floor grid. The 2 min-1 sec shock paradigm was repeated for a total of 3 shocks. 1 min after the last shock, animals were removed to their homecage. RNA was extracted was extracted 1hr, 2hr, 4hr, and 6hr after the last shock treatment. Keywords: time-course

C+S：情境+电击。选取年轻雄性C57BL/6J小鼠，使其暴露于情境恐惧条件反射范式，该范式流程如下：将小鼠置于全新空间环境中2分钟；2分钟后，通过地板格栅施加1秒（0.5毫安）的电击。上述2分钟环境暴露+1秒电击的流程总计重复3次。末次电击结束1分钟后，将小鼠转移至其饲养笼。分别于末次电击处理后1小时、2小时、4小时及6小时提取RNA。关键词：时间进程。