Local ancestry accuracy in simulations of African Americans, Mexicans and Puerto Ricans.

Accuracy is reported as mean r2 (haploid accuracy, diploid accuracy). “Array data” denotes that a method was run only on the variants present on the Illumina 1 M genotyping array. “Full genome” denotes methods were run using all the variants. RFMix requires phased haplotype input that was phased using Beagle; all other methods received unphased genotype data as input. Correlation values are the mean squared correlation across SNPs of the true vs. inferred ancestry across individuals. Accuracy is reported as mean r2 (haploid accuracy, diploid accuracy). LAMP-LD and MULTIMIX were optimized to run with genotyping array data, possibly explaining the steep drop in accuracy when they are run using full sequencing data.

精度以平均决定系数（r²）报告，涵盖单倍体型精度与二倍体型精度。"阵列数据（Array data）"指代仅针对Illumina 1M基因分型阵列（Illumina 1 M genotyping array）上存在的变异实施分析的方法。"全基因组（Full genome）"指代采用全部变异开展分析的方法。RFMix需依赖经Beagle定相的单倍型输入数据，其余所有方法均以未定相基因型数据作为输入。相关性值为所有个体中真实祖先信息与推断祖先信息之间，跨单核苷酸多态性（Single Nucleotide Polymorphism，SNP）的均方相关性。精度以平均决定系数（r²）报告，涵盖单倍体型精度与二倍体型精度。LAMP-LD与MULTIMIX已针对基因分型阵列数据完成优化，这或可解释当采用全测序数据运行时，其精度出现大幅下降的原因。