Social Brain Freesurfer ROIs

This fileset contains eight Freesurfer annot files for four social brain regions of interest (ROI). Social brain regions of interest include medial Brodmann Area 10 (mBA10), temporoparietal junction (TPJ), posterior superior temporal sulcus (pSTS) and anterior temporal cortex (ATC). Details regarding the definition of the ROIs are described here: doi:10.1093/scan/nss113. In brief: The medial portion of BA10 was defined using the PALS B12 Brodmann atlas projected onto an averaged Freesurfer template (Van Essen, 2005). From this atlas, the BA10 label was selected, and any area of this label located outside of the medial cortex was eliminated. The TPJ was defined using the border coordinates of a functional subdivision generated in a previous study (Mars et al., 2012). This study defined three consistent functional subregions within a larger TPJ area in the right hemisphere, each with unique functional and structural connectivity profiles. Of the three subregions, we chose to use the posterior TPJ subregion, as it was functionally connected to other areas of the social brain, such as mBA10 and ATC (Mars et al., 2012). The pSTS region was created by extending the Desikan-Killiany Atlas defined bank STS (Fischl et al., 2004; Desikan et al., 2006) to the border of the TPJ. The ATC was defined by extending the temporal pole, defined as Brodmann Area 38 in the PALS B12 Brodmann atlas, back to include areas of the ATC recruited during mentalizing tasks in previous fMRI studies (see Olson et al., 2007 for a review). *** For those of you experiencing holes in your labels **** A few people have contacted me about seeing holes in their label files when applying these regions to participants with Freesurfer. I had a similar problem when I used the Freesurfer mri_label2label command. The way to avoid this issue is to use the mri_surf2surf command. Here's an example of the code: mri_surf2surf --srcsubject fsaverage --trgsubject $SUBJID --hemi lh --sval-annot $SUBJECTS_DIR/SCAN2012ANNOT/lh.TPJ.annot --tval lh.TPJ.annot You can extract the measurements from the annot mris_anatomical_stats command (use the -a option).本数据集包含8个FreeSurfer（FreeSurfer）注释文件，对应4个社交脑感兴趣区（Region of Interest，ROI）。社交脑感兴趣区包括内侧布罗德曼10区（medial Brodmann Area 10，mBA10）、颞顶联合区（Temporoparietal Junction，TPJ）、后颞上沟（Posterior Superior Temporal Sulcus，pSTS）以及前颞叶皮层（Anterior Temporal Cortex，ATC）。 有关这些感兴趣区的定义细节，请参见文献：doi:10.1093/scan/nss113。 简言之：BA10的内侧部分通过映射至平均化FreeSurfer模板的PALS B12布罗德曼图谱进行定义（Van Essen，2005）。从该图谱中选取BA10标签，并剔除该标签中位于内侧皮层之外的区域。 颞顶联合区（TPJ）的定义基于既往研究中生成的功能亚区边界坐标（Mars等，2012）。该研究在右侧大脑半球的更大范围颞顶联合区内定义了3个稳定的功能亚区，每个亚区均具备独特的功能与结构连接特征。在这3个亚区中，我们选取了后颞顶联合亚区，因其与内侧布罗德曼10区、前颞叶皮层等社交脑其他区域存在功能连接（Mars等，2012）。 后颞上沟（pSTS）区域的构建方式为：将德西坎-基利安图谱（Desikan-Killiany Atlas）所定义的颞上沟沟岸（Fischl等，2004；Desikan等，2006）延伸至颞顶联合区边界。 前颞叶皮层（ATC）的定义方式为：将PALS B12布罗德曼图谱中标记为布罗德曼38区的颞极向后延伸，纳入既往功能磁共振成像（functional magnetic resonance imaging，fMRI）研究中心理理论任务所激活的前颞叶皮层区域（详见Olson等，2007的综述）。 ***针对部分用户出现的标签孔洞问题*** 已有多位用户反馈，在将上述感兴趣区应用于FreeSurfer处理的被试数据时，其标签文件会出现孔洞。本人在使用FreeSurfer的mri_label2label命令时也曾遇到过同类问题。规避该问题的方法为使用mri_surf2surf命令。以下为代码示例： mri_surf2surf --srcsubject fsaverage --trgsubject $SUBJID --hemi lh --sval-annot $SUBJECTS_DIR/SCAN2012ANNOT/lh.TPJ.annot --tval lh.TPJ.annot 可通过annot mris_anatomical_stats命令提取测量值（需使用-a选项）。