emmetaobrien/mm_neo_atlas: Transcriptomic Atlas of Mouse Neocortical Layers

In the mammalian cortex, neurons and glia form a patterned structure across six layers whose complex cytoarchitectonic arrangement is likely to contribute to cognition. This dataset contains transcriptomes from layers 1-6b of different areas (primary and secondary) of the adult (postnatal day 56) mouse somatosensory cortex. A total of 5,835 protein-coding genes and 66 noncoding RNA loci are differentially expressed ("patterned") across the layers. Layers 2-6b are each associated with specific functional and disease annotations that provide insights into their biological roles. This dataset extends currently available resources by providing quantitative expression levels, by being genome-wide, by including novel loci, and by identifying candidate alternatively spliced transcripts that are differentially expressed across layers. "A transcriptomic atlas of mouse neocortical layers", TG Belgard et al. Neuron, 25:605-616 (2011). http://wwwfgu.anat.ox.ac.uk/~grantb/mouse_layers/