I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus
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In the nucleus, inositol polyphosphate multikinase (IPMK) phosphorylates inositol 1,3,4,6-tetrakisphosphate (I(1,3,4,6)P4) to inositol 1,3,4,5,6-pentakisphosphate (I(1,3,4,5,6)P5) (Chang et al. 2002, Chang & Majerus 2006).
在细胞核中,肌醇多磷酸多激酶(Inositol polyphosphate multikinase,IPMK)将肌醇1,3,4,6-四磷酸(Inositol 1,3,4,6-tetrakisphosphate,I(1,3,4,6)P4)磷酸化为肌醇1,3,4,5,6-五磷酸(Inositol 1,3,4,5,6-pentakisphosphate,I(1,3,4,5,6)P5)(Chang 等人,2002年,Chang 与 Majerus,2006年)。
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