Single-cell RNA/ATAC multiomic analysis of TRM and ReCirulating CD8+ T cells from HGSOC tumors

Purpose: Evaluation of the BCR profile of HGSOC associated/infiltrated B cells We isolated TRM and ReCirulating CD8+ T cells from X HGSOC disscociated tumors and performed 10X Multiome ATAC + Gene Expression

研究目的：评估与高级别浆液性卵巢癌（High-Grade Serous Ovarian Cancer, HGSOC）相关或浸润性B细胞的B细胞受体（B Cell Receptor, BCR）谱系。本研究从X例解离后的高级别浆液性卵巢癌肿瘤组织中分离出组织驻留记忆T细胞（Tissue Resident Memory T cells, TRM）与循环CD8阳性T细胞，并开展了10×多组学ATAC+基因表达（10X Multiome ATAC + Gene Expression）检测。