Affinities and melting temperatures (T_m) for the non-randomized albumin-binding domain (ABD), ADAPT_ERBB2-1 and variants of ADAPT_ERBB2-1.

Kinetic parameters are presented as mean values with standard deviation. KD was calculated from the rate constants (kd/ka) and the number of replicates for each variant is indicated within brackets. No binding to ERBB2 could be observed, even at elevated concentrations, for the negative control ABD or the four variants T7A, Y10A, H11A and Y38A. Melting temperatures (Tm) from CD measurements are also included.动力学参数以平均值±标准差的形式呈现。解离常数（KD）由速率常数（kd/ka）计算得出，各变体的重复实验次数以括号标注。阴性对照ABD以及T7A、Y10A、H11A、Y38A四个变体，即便在升高的浓度条件下，也未检测到与人表皮生长因子受体2（ERBB2）的结合。圆二色谱（CD）测得的解链温度（Tm）亦一并纳入本数据集。