DA-2P

DA-2P investigates the impact of Lactobacillus paracasei treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample DA-2P:<br>D: Denotes the strain ST-4 of Clostridioides difficile.<br>A: Represents timepoint 1, indicating sampling before C. difficile infection.<br>2: Refers to the specific mouse number under investigation.<br>P: Indicates the treatment administered, which in this case is Lactobacillus paracasei.

数据集DA-2P旨在探究副干酪乳杆菌（Lactobacillus paracasei）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。研究人员对感染后小鼠的粪便样本采用Invitrogen试剂完成前处理，并通过Ion Torrent下一代测序（NGS）系统进行测序。借助Ion Reporter SW（16S）开展分析后，结果显示感染后第1、3、6天的微生物类群动态均发生显著偏移，该发现为阐明益生菌在艰难梭菌感染期间调控肠道菌群的潜在作用提供了重要依据。<br>关于样本DA-2P的命名说明：<br>D：指代艰难梭菌（Clostridioides difficile）菌株ST-4；<br>A：代表采样时间点1，即艰难梭菌感染前的采样节点；<br>2：指代本次研究中的特定小鼠编号；<br>P：代表所施加的干预手段，本研究中为副干酪乳杆菌处理。