Impact of fecal microbiota transplantation (FMT) in 3 days-ABX-treated recipient mice using feces from 6 NSCLC patients at diagnosis.

This study aimed to analyze changes in gut microbiota composition in mice after transplantation of fecal microbiota (FMT, N = 6) from the feces of NSCLC patients by analyzing fecal content using 16S rRNA sequencing, 10 days after transplantation. Specific-pathogen-free (SPF) mice were used for each experiments (N=4) as controls.

本研究旨在探究接受非小细胞肺癌（non-small cell lung cancer, NSCLC）患者粪便来源粪菌移植（fecal microbiota transplantation, FMT，样本量N=6）的小鼠，在移植后10天的肠道菌群组成变化，实验采用16S rRNA测序（16S rRNA sequencing）技术对粪便内容物进行检测分析。本研究各实验均以无特定病原体（specific-pathogen-free, SPF）小鼠作为对照，对照组样本量为N=4。