Mineral Metabolism.

Calcium (Ca) and Creatinine were measured in serum and urine and 25-Hydroxy Vitamin D (25(OH)D3) was measured in serum from 14-week old mice that had been treated with vehicle (veh), a single Lactobacillus (L) strain (L. para) or a mixture of three strains (L. mix) during 6 weeks, starting two weeks before ovx or sham surgery. Results are given as mean±SEM, (n = 5–10). ** p≤0.01, * p≤0.05, Students t test ovx vs. sham, # p≤0.05, ANOVA followed by Dunnett's post hoc test within the groups, ovx L. Para and L. mix vs. ovx veh.本研究对14周龄小鼠的血清与尿液样本中的钙（Calcium, Ca）和肌酐（Creatinine）进行了定量检测，并对其血清样本中的25-羟维生素D₃（25-Hydroxy Vitamin D, 25(OH)D3）开展了定量检测。实验小鼠在去卵巢手术（ovariectomy, ovx）或假手术（sham surgery）前两周开始，分别接受为期6周的溶剂（vehicle, veh）、单株乳酸杆菌（Lactobacillus, L）菌株（L. para）或三株混合乳酸杆菌（L. mix）干预。实验结果以平均值±标准误（standard error of the mean, SEM）表示，每组样本量n=5~10。统计学显著性标注说明：**p≤0.01、*p≤0.05为ovx组与sham组间采用两独立样本Student t检验得到的结果；#p≤0.05为ovx组内的比较结果，即ovx L. para组、ovx L. mix组与ovx veh组间经单因素方差分析（ANOVA）后行Dunnett事后检验得到的结果。