The 5-HT₇ specific antagonist SB258719 does not affect olfaction.

Untreated and SB-treated (3.0 mM) flies were assayed for olfactory avoidance and sensitivity at different concentrations of the odors methylcyclohexanhol (MCH) and benzaldehyde (BA). The performance indices (PI) of the SB-treated flies are equivalent to control flies at all concentrations.将未经处理与经3.0 mM SB处理的果蝇，以不同浓度的气味物质甲基环己醇（methylcyclohexanhol，MCH）与苯甲醛（benzaldehyde，BA）为嗅觉刺激底物，分别检测其嗅觉回避行为与嗅觉敏感性。经3.0 mM SB处理的果蝇的行为表现指数（performance index，PI）在所有测试浓度下均与对照组果蝇相当。