Additional file 1 of Genome-wide analysis of retinal transcriptome reveals common genetic network underlying perception of contrast and optical defocus detection

Additional file 1: Table S1. Refractive errors in mice comprising collaborative cross (P40, diopters). Table S2. Form-deprivation myopia in mice comprising collaborative cross (deprived eye versus control eye, diopters). Table S3. Contrast sensitivity in mice comprising collaborative cross. Table S4. Genes whose expression correlates with refractive error in mice comprising collaborative cross (FC = fold change, hyperopia versus myopia). Table S5. Genes whose expression correlates with susceptibility to myopia in mice comprising collaborative cross (FC = fold change, high versus low myopia). Table S6. Genes whose expression correlates with contrast sensitivity in mice comprising collaborative cross (FC = fold change, high versus low contrast sensitivity). Table S7. Gene ontology categories associated with genes whose expression correlates with refractive error in mice comprising collaborative cross (BP, biological process; CC, cellular component; MF, molecular function). Table S8. Gene ontology categories associated with genes whose expression correlates with susceptibility to myopia in mice comprising collaborative cross (BP, biological process; CC, cellular component; MF, molecular function). Table S9. Gene ontology categories associated with genes whose expression correlates with contrast sensitivity in mice comprising collaborative cross (BP, biological process; CC, cellular component; MF, molecular function). Table S10. Canonical pathways associated with genes whose expression correlates with refractive error in mice comprising collaborative cross. Table S11. Canonical pathways associated with genes whose expression correlates with susceptibility to myopia in mice comprising collaborative cross. Table S12. Canonical pathways associated with genes whose expression correlates with contrast sensitivity in mice comprising collaborative cross. Table S13. Genes whose expression correlates with both contrast sensitivity and refractive error in mice comprising collaborative cross (FC = fold change, contrast sensitivity = high versus low contrast sensitivity, RE = hyperopia versus myopia). Table S14. Genes whose expression correlates with both contrast sensitivity and susceptibility to myopia in mice comprising collaborative cross (FC = fold change, contrast sensitivity = high versus low contrast sensitivity, myopia = high versus low myopia). Table S15. Gene ontology categories associated with genes whose expression correlates with both contrast sensitivity and refractive error in mice comprising collaborative cross (BP, biological process; CC, cellular component; MF, molecular function). Table S16. Gene ontology categories associated with genes whose expression correlates with both contrast sensitivity and susceptibility to myopia in mice comprising collaborative cross (BP, biological process; CC, cellular component; MF, molecular function). Table S17. Genes whose expression correlates with both contrast sensitivity and refractive error in mice comprising collaborative cross and linked to human diseases (FC = fold change, high versus low contrast sensitivity). Table S18. Genes whose expression correlates with both contrast sensitivity and susceptibility to myopia in mice comprising collaborative cross and linked to human diseases (FC = fold change, high versus low contrast sensitivity). (XLS 898 KB)附加文件1：表S1 协作杂交（Collaborative Cross, CC）小鼠的屈光不正（P40，屈光度）。 表S2 协作杂交小鼠的形觉剥夺性近视（剥夺眼与对照眼，屈光度）。 表S3 协作杂交小鼠的对比敏感度。 表S4 协作杂交小鼠中表达水平与屈光不正相关的基因（FC=倍数变化（fold change），远视 vs 近视）。 表S5 协作杂交小鼠中表达水平与近视易感性相关的基因（FC=倍数变化，高度近视 vs 低度近视）。 表S6 协作杂交小鼠中表达水平与对比敏感度相关的基因（FC=倍数变化，高对比敏感度 vs 低对比敏感度）。 表S7 与协作杂交小鼠中表达水平与屈光不正相关的基因相关的基因本体（Gene Ontology, GO）类别（BP=生物过程（Biological Process）；CC=细胞组分（Cellular Component）；MF=分子功能（Molecular Function））。 表S8 与协作杂交小鼠中表达水平与近视易感性相关的基因相关的基因本体类别（BP=生物过程；CC=细胞组分；MF=分子功能）。 表S9 与协作杂交小鼠中表达水平与对比敏感度相关的基因相关的基因本体类别（BP=生物过程；CC=细胞组分；MF=分子功能）。 表S10 与协作杂交小鼠中表达水平与屈光不正相关的基因相关的经典通路。 表S11 与协作杂交小鼠中表达水平与近视易感性相关的基因相关的经典通路。 表S12 与协作杂交小鼠中表达水平与对比敏感度相关的基因相关的经典通路。 表S13 协作杂交小鼠中表达水平同时与对比敏感度和屈光不正相关的基因（FC=倍数变化，对比敏感度=高对比敏感度 vs 低对比敏感度，RE=远视 vs 近视）。 表S14 协作杂交小鼠中表达水平同时与对比敏感度和近视易感性相关的基因（FC=倍数变化，对比敏感度=高对比敏感度 vs 低对比敏感度，近视=高度近视 vs 低度近视）。 表S15 与协作杂交小鼠中表达水平同时与对比敏感度和屈光不正相关的基因相关的基因本体类别（BP=生物过程；CC=细胞组分；MF=分子功能）。 表S16 与协作杂交小鼠中表达水平同时与对比敏感度和近视易感性相关的基因相关的基因本体类别（BP=生物过程；CC=细胞组分；MF=分子功能）。 表S17 协作杂交小鼠中表达水平同时与对比敏感度和屈光不正相关，且与人类疾病相关的基因（FC=倍数变化，高对比敏感度 vs 低对比敏感度）。 表S18 协作杂交小鼠中表达水平同时与对比敏感度和近视易感性相关，且与人类疾病相关的基因（FC=倍数变化，高对比敏感度 vs 低对比敏感度）。(XLS 898 KB)