Danio rerio strain:AB strain Transcriptome or Gene expression. Danio rerio strain:AB strain

Mercury is a widespread toxicant in aquatic environment that can cause deleterious effects on fish. Although a number of mercury-regulated genes have been investigated in adult fish, the transcriptional responses of fish embryos to acute mercury exposure are not well understood. In this study, RNA sequencing was used to examine the transcriptional changes in developing zebrafish under a low concentration of mercury exposure from 24 to120 hpf. Our results provide useful insights to help further understand the transcriptional response and detoxification ability of zebrafish embryos following acute exposure to mercury.

汞是水生环境中广泛分布的有毒污染物，可对鱼类产生有害效应。尽管已有多项研究针对成鱼体内的汞调控基因展开了探索，但鱼类胚胎在急性汞暴露下的转录响应仍未得到充分阐明。本研究采用RNA测序（RNA sequencing）技术，对低浓度汞暴露下、受精后24至120小时的发育斑马鱼的转录变化进行了检测。本研究结果可为深入解析斑马鱼胚胎在急性汞暴露后的转录响应与解毒能力提供有价值的参考依据。