Increased pathogenic T cells in SR-A−/− NOD mice treated with poly(I∶C).

(A) The number (percentage) of CD4+CD25+ T cells was higher in SR-A−/− NOD mice (6 weeks of age) treated with poly(I∶C) (n = 3) than in untreated SR-A−/− NOD mice (n = 7), suggesting that CD4+CD25+ T cells mainly comprised pathogenic T cells. mean ± SD. * p value = 0.0167. (B) The number (percentage) of CD4+Foxp3+ T cells in SR-A−/− NOD mice (6 weeks of age) treated with poly(I∶C) (n = 3) was similar to that in untreated SR-A−/− NOD mice (n = 7), mean ± SD. p value = 0.5167.(A) 经聚肌苷酸-聚胞苷酸（poly(I∶C)）处理的6周龄清道夫受体A基因敲除非肥胖糖尿病（SR-A⁻/⁻ NOD）小鼠（n=3）中，CD4+CD25+ T细胞的数量（占比）高于未处理的同品系小鼠（n=7），提示CD4+CD25+ T细胞主要为致病性T细胞。数据以平均值±标准差（mean ± SD）表示，*p值=0.0167。(B) 经聚肌苷酸-聚胞苷酸（poly(I∶C)）处理的6周龄SR-A⁻/⁻ NOD小鼠（n=3）中，CD4+Foxp3+ T细胞的数量（占比）与未处理的同品系小鼠（n=7）无统计学差异，数据以平均值±标准差（mean ± SD）表示，p值=0.5167。