CK-2B

CK-2B investigates the impact of Bifidobacterium bifidum treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample CK-2B :<br>C: Denotes the strain ST-2 of Clostridioides difficile.<br>K: Represents timepoint 3, indicating sampling after treatment.<br>2: Refers to the specific mouse number under investigation.<br>B: Indicates the treatment administered, which in this case is Bifidobacterium bifidum.

CK-2B数据集旨在探究双歧杆菌（Bifidobacterium bifidum）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的调控效应。本研究采集了感染建模后小鼠的粪便样本，采用Invitrogen相关试剂完成样本前处理，并在Ion Torrent下一代测序（NGS）系统上完成高通量测序。通过Ion Reporter SW（16S）分析工具开展菌群分析后，结果揭示了感染后第1、3、6天的微生物类群动态变化特征，为阐明艰难梭菌感染期间益生菌调控肠道菌群的潜在价值提供了实验依据。

样本CK-2B的标识含义如下：
C：代表所使用的艰难梭菌菌株为ST-2；
K：表示采样时间点为干预后第3天；
2：指代本次研究中的特定实验小鼠编号；
B：代表本次施加的干预措施为双歧杆菌处理。