Post challenge survival plots for inactivated vaccines.

Kaplan Meyer's (KM) post challenge survival percentages (PCSPs) of fish vaccinated with inactivated, water-in-oil adjuvanted vaccines made from the TAT, TTT, PAA and PTA strains, challenged at 10 weeks post vaccination with the virulent TAT strain. Mortality started on day 11 post challenge and stopped on day 27 when fish stopped dying and the PCSP curves plateaued. The challenge study was stopped on day 31. TAT and TTT groups overlap while there was a reduced survival in the PTA and PAA groups with significantly lower PCSP for the latter (p = 0.042).

本数据集记录了经TAT、TTT、PAA及PTA菌株制备的灭活水油佐剂疫苗免疫的鱼类，其攻毒后存活率（post challenge survival percentages, PCSPs）的卡普兰-迈耶（Kaplan Meyer, KM）分析结果。试验于免疫后10周使用强毒TAT菌株对免疫鱼群开展攻毒：攻毒后第11天开始出现鱼类死亡，第27天鱼群停止死亡且PCSP曲线趋于平稳，攻毒试验于第31天正式终止。结果显示，TAT组与TTT组的PCSP曲线相互重合；PTA组与PAA组的存活率均有所下降，其中PAA组的PCSP显著更低（p=0.042）。