Additional file 3 of Metabolomics- and proteomics-based multi-omics integration reveals early metabolite alterations in sepsis-associated acute kidney injury

Additional file 3. Renal proteomics analysis. Table S1. Differential renal proteins between SA-AKI and sepsis in mice. Figure S1. Mice renal proteins and enrichment analysis. a) Abundance distributions of mice renal metabolomics and proteomics. b) Heatmap showing the correlation between renal proteins and the three biochemical indicators. Orange indicates a positive correlation and blue indicates a negative correlation. c-e) Gene Ontology Enrichment Analysis for renal differential proteins, including biological process (BP) (c); cell composition (CC) (d); molecular functional (MF) (e).附加文件3：肾脏蛋白质组学分析。 表S1：小鼠脓毒症相关性急性肾损伤（SA-AKI）与脓毒症之间的差异肾脏蛋白质。 图S1：小鼠肾脏蛋白质及富集分析。 a) 小鼠肾脏代谢组学（metabolomics）与蛋白质组学（proteomics）的丰度分布。 b) 热图展示肾脏蛋白质与三项生化指标间的相关性：橙色代表正相关，蓝色代表负相关。 c-e) 肾脏差异蛋白质的基因本体（Gene Ontology，GO）富集分析，包括：(c) 生物过程（BP）；(d) 细胞组分（CC）；(e) 分子功能（MF）。