Genome-wide analysis of gene expression in mouse pancreas tumors [FAP and aSMA depletion]. Genome-wide analysis of gene expression in mouse pancreas tumors [FAP and aSMA depletion]

Gene expression analysis of pancreatic tumors from genetically engineered mice (Pdx-Cre;LSL-KRASG12D;TGFBRIIf/f) with depletion of aSMA+ or FAP+ cells. The pancreas tumors were harvested and analysed for gene expression profiles comparisons. Overall design: Total RNA was isolated from the pancreas tumors of 3 PKT FAP control mice, 3 PKT FAP depleted mice, 3 PKT aSMA control mice, 3 PKT aSMA depleted mice

本数据集针对携带α平滑肌肌动蛋白阳性（aSMA+）或成纤维细胞活化蛋白阳性（FAP+）细胞清除改造的基因工程小鼠（Pdx-Cre;LSL-KRASG12D;TGFBRIIf/f）的胰腺肿瘤开展基因表达分析。研究人员收集上述胰腺肿瘤样本，对其基因表达谱进行比较分析。整体实验设计：从3只PKT FAP对照组小鼠、3只PKT FAP细胞清除组小鼠、3只PKT aSMA对照组小鼠、3只PKT aSMA细胞清除组小鼠的胰腺肿瘤中提取总RNA。