Mus musculus strain:C57BL/6J Genome sequencing. Mus musculus strain:C57BL/6J

To identify genomic variants involved in drug resistance, we performed whole genome sequencing of Eμ-Myc Cdkn2a-/- lymphoma cells with resistance to mafosfamide via dose escalation.为鉴定参与药物耐药性的基因组变异，我们通过剂量递增法构建了对马法司他丁（mafosfamide）耐药的Eμ-Myc Cdkn2a-/-淋巴瘤细胞，并对其开展了全基因组测序（whole genome sequencing）。