Tables of human adipose tissue cell type-specific genes

The data set includes:1) "Celltype_enriched.txt" files separated by ";" that contain genes significantly enriched in one cell type compared to other three analyzed hWAT cell types according to the analysis described in R markdown file:http://figshare.com/s/509ea9441af442a735acAdjusted p-value &lt;0.05 for all pairwise comparisons, moderated F-statistics p-value &lt;0.05 (from R package/bioconductor package Limma).<br>2) "Celltype_enriched_collected.txt" files separated by ";". These files contain tables that include mean expression of the gene in a fraction where it is enriched, log fold change (logFC) and adjusted P values (adj.P.val) compared to each of other fractions. Minimal logFC and maximal adj.P.Val against other fractions are included as separate columns to enable easy sorting of the data in search for best expressed, best enriched or most specific genes. <br>3) R-code used to generate "Celltype_enriched_collected.txt" tables is provided.<br>4) In addition, a table with 100 highest-ranked genes from each fraction (based on highest logFC_min and lowest adj.P.val_max) is also included ("Selected_enriched_genes_all_fractions" - separated by tab).

本数据集包含以下内容：
1) 以分号分隔的"Celltype_enriched.txt"文件：根据R Markdown文档（http://figshare.com/s/509ea9441af442a735ac）中描述的分析方法，这些文件收录了相较于其余三种已分析的人类白色脂肪组织（hWAT）细胞类型，在单一种类细胞中显著富集的基因。所有成对比较的校正后P值均小于0.05，经校正的F统计量P值同样小于0.05（分析工具来自R包/生物导体包Limma）。
2) 以分号分隔的"Celltype_enriched_collected.txt"文件：此类文件包含数据表，其中记录了基因在其富集的细胞组分中的平均表达量、对数倍变化值（log fold change, logFC），以及相较于其他每一种细胞组分的校正后P值（adj.P.Val）。数据表中额外增设两列，分别为针对其余所有细胞组分的最小logFC值与最大校正后P值，以便于快速对数据进行排序，筛选出表达最优、富集最佳或特异性最强的基因。
3) 本数据集附带了用于生成"Celltype_enriched_collected.txt"数据表的R代码。
4) 此外，本数据集还包含一张数据表：基于「最高最小logFC值与最低最大校正后P值」的筛选标准，从每一种细胞组分中选取的前100个排名最高的富集基因（文件名为"Selected_enriched_genes_all_fractions"，以制表符分隔）。