SAS format library in SAS dataset format in The BioCycle Study

SAS format library in SAS dataset format
Study Description
The BioCycle Study is a prospective cohort study completed at the University at Buffalo and offers a unique and comprehensive assessment of menstrual cycle function. The primary goal of the BioCycle Study was to better understand the intricate relationship between reproductive hormone levels and oxidative stress during the menstrual cycle. Multiple markers of oxidative stress, reproductive hormones, inflammation, and metabolic biomarkers were measured in a cohort of 259 women of reproductive age over the course of two menstrual cycles. Fertility monitors were utilized to time the subjects' visits to ensure appropriate timing of biospecimen collection. Additional information regarding diet, lifestyle, and physical measurements was obtained throughout the study via standardized questionnaires, anthropometric assessments, and daily diaries. Participants were highly adherent to the study protocol, with 94% of all women completing seven or eight visits per cycle. Regularly menstruating premenopausal female volunteers aged 18–44 years from the western New York state region.

本数据集为采用SAS数据集格式存储的SAS格式库。

研究概况
生物周期研究（BioCycle Study）是一项由布法罗大学（University at Buffalo）完成的前瞻性队列研究，对月经周期功能开展了独具特色且全面的评估。本研究的核心目标为深入阐明月经周期内生殖激素水平与氧化应激之间的复杂关联。研究团队在两个月经周期内，对259名育龄女性组成的队列完成了氧化应激、生殖激素、炎症及代谢生物标志物的多项指标检测。研究使用排卵监测仪（Fertility monitors）规划受试者的随访时间，以确保生物样本采集的时机精准适宜。研究期间，研究人员还通过标准化问卷、人体测量学评估及每日日记，收集了受试者的饮食、生活方式及身体测量相关的额外信息。本研究对象依从性极高，94%的女性在每个月经周期完成7或8次随访。本研究的招募对象为纽约州西部地区、年龄介于18至44岁之间、月经规律的绝经前女性志愿者。