Traveling Heads Quantitative MRI 7T Dataset

MRI Datasets from the GUFI Traveling Heads experiment at 7T.

2 Subjects
10 Sites

The same quantitative imaging protocol at all sites consisting of:

B1 and B0 mapping
MP2RAGE
QSM
CEST
Relaxometry

The sites were organized in the German Ultrahigh Field Imaging network (GUFI, www.mr-gufi.de) and discriminate by hard- and software differences of the 7T systems from different generations (same vendor):
Configuration 1:
Magnet: Passively shielded, Gradient Coil: 38mT/m, RFPA: 8kW, RF Coil: 24ch, Software: VB
Datasets: BER_20181211, HEI_20190205
Configuration 2:
Magnet: Passively shielded, Gradient Coil: 38mT/m, RFPA: 8kW, RF Coil: 32ch, Software: VB
Datasets: ES_20181008, ES_20190813
Configuration 3:
Magnet: Passively shielded, Gradient Coil: 70mT/m, RFPA: 8kW, RF Coil: 32ch, Software: VB
Datasets: MAG_20190114, LEI_20190115, WIE_20190404
Configuration 4:
Magnet: Actively shielded, Gradient Coil: 70mT/m, RFPA: 8kW, RF Coil: 32ch, Software: VB
Datasets: BN_20181009
Configuration 5:
Magnet: Actively shielded, Gradient Coil: 80mT/m, RFPA: 11kW, RF Coil: 32ch, Software: VE
Datasets: ERL_20181019, ERL_20190226, ERL_20190618, JUL_20181212, JUL_20190604, WUE_20190125, WUE_20190617

One full dataset includes:

b0fieldHZ:  B0 field mapped in Hz

b1map_mtflash_reg:  rel. B1 map registered to the mtflash dataset for B1 correction of relaxometry data

b1rel:  rel. B1 map original image space (100*measured flip/nominal flip)

brainmask_mp2rage:  brain mask calculated with CBS tools, ANTS and FSL for MP2RAGE data

CEST_NOE:  rNOE map derived from the CEST analysis

CEST_APT:  APT map derived from the CEST analysis

CEST_MT:  MT map derived from the CEST analysis

CEST3D06:  CEST image data for B1=0.6uT

CEST3D06:  CEST image data for B1=0.9uT

CEST3DWASABI:  Correction data for the CEST calculation

gre_qsm:  QSM Map calculated from the GRE data in ppB

gre_qsm_mag:  Multiecho-GRE magnitude image data for QSM

gre_qsm_phs:  Multiecho-GRE phase image data for QSM

mp2rage_inv1:  MP2RAGE image data first inversion contrast

mp2rage_inv2:  MP2RAGE image data second inversion contrast

mp2rage_T1_corr:  MP2RAGE derived T1 map after additional transmit B1 correction with B1 data

mp2rage_T1_gdc_brain:  MP2RAGE T1 map after brain extraction and gradient distortion correction (used for inter-site comparisons)

mp2rage_uni_corr:  MP2RAGE uniform images after additional transmit B1 correction with B1 data

mp2rage_uni_gdc_brain:  MP2RAGE uniform images after brain extraction and gradient distortion correction (used for inter-site comparisons)

mpm_PD:  Proton Density map (in %) derived from the multiparametic analysis of the mtflash data

mpm_T1:  T1 map (in s) derived from the multiparametic analysis of the mtflash data

mpm_T2s:  T2* map (in ms) derived from the multiparametic analysis of the mtflash data

mtflash3dPD:  Multiecho FLASH images in PD weighting for multiparametic analysis

mtflash3dT1:  Multiecho FLASH images in T1 weighting for multiparametic analysis

Not all data may be available for every measurement.

For further information on the dataset and the methods used for analysis please refer to the corresponding paper:
M. N. Voelker et al., “The Traveling Heads 2.0: Multicenter Reproducibility of Quantitative Imaging Methods at 7 Tesla,” Neuroimage, p. 117910, Feb. 2021.
https://doi.org/10.1016/j.neuroimage.2021.117910
Please cite if you use the GUFI data!

The first upload (TH2_data_ES_s1.zip) consists of the one full dataset derived at the first measurement at configuration 2 of subject 1 and was intended for the review process (CEST results of this upload were refined during review) of the corresponding paper.
The full dataset (TH2_alldata.zip) was uploaded as an update under this project number.

7特斯拉（7T）磁共振成像（Magnetic Resonance Imaging, MRI）数据集源自GUFI旅行头部实验。

本数据集包含2名受试者、10个扫描中心的影像数据，所有扫描中心均采用统一的定量成像协议，具体包括：B1与B0场图扫描、MP2RAGE序列扫描、定量磁化率映射（Quantitative Susceptibility Mapping, QSM）、化学交换饱和转移（Chemical Exchange Saturation Transfer, CEST）分析以及弛豫测量。

所有扫描中心均隶属于德国超高场成像网络（German Ultrahigh Field Imaging Network, GUFI，网址：www.mr-gufi.de），各中心的7T磁共振系统来自同一厂商，但分属不同代际，硬件与软件配置存在差异，具体分为以下5类配置：

配置1：
磁体：被动屏蔽型；梯度线圈：38毫特斯拉/米；射频功率放大器（Radio Frequency Power Amplifier, RFPA）：8千瓦；射频线圈：24通道；软件版本：VB
对应数据集：BER_20181211、HEI_20190205

配置2：
磁体：被动屏蔽型；梯度线圈：38毫特斯拉/米；RFPA：8千瓦；射频线圈：32通道；软件版本：VB
对应数据集：ES_20181008、ES_20190813

配置3：
磁体：被动屏蔽型；梯度线圈：70毫特斯拉/米；RFPA：8千瓦；射频线圈：32通道；软件版本：VB
对应数据集：MAG_20190114、LEI_20190115、WIE_20190404

配置4：
磁体：主动屏蔽型；梯度线圈：70毫特斯拉/米；RFPA：8千瓦；射频线圈：32通道；软件版本：VB
对应数据集：BN_20181009

配置5：
磁体：主动屏蔽型；梯度线圈：80毫特斯拉/米；RFPA：11千瓦；射频线圈：32通道；软件版本：VE
对应数据集：ERL_20181019、ERL_20190226、ERL_20190618、JUL_20181212、JUL_20190604、WUE_20190125、WUE_20190617

一套完整数据集包含以下内容：
b0fieldHZ：以赫兹为单位的B0场分布图
b1map_mtflash_reg：配准至mtflash数据集的相对B1图，用于弛豫测量数据的B1校正
b1rel：原始图像空间下的相对B1图（计算公式为100×实测翻转角/标称翻转角）
brainmask_mp2rage：基于CBS工具、ANTS与FSL软件针对MP2RAGE数据生成的脑区掩膜
CEST_NOE：从CEST分析中得到的反式NOE图
CEST_APT：从CEST分析中得到的酰胺质子转移（Amide Proton Transfer, APT）图
CEST_MT：从CEST分析中得到的磁化传递（Magnetization Transfer, MT）图
CEST3D06：B1场强为0.6微特斯拉的3D CEST图像数据
CEST3D06：B1场强为0.9微特斯拉的3D CEST图像数据
CEST3DWASABI：用于CEST计算的校正数据
gre_qsm：从梯度回波（Gradient Recalled Echo, GRE）数据中计算得到的、以ppB为单位的QSM图
gre_qsm_mag：用于QSM计算的多回波GRE幅值图像数据
gre_qsm_phs：用于QSM计算的多回波GRE相位图像数据
mp2rage_inv1：MP2RAGE序列的第一次反转对比图像数据
mp2rage_inv2：MP2RAGE序列的第二次反转对比图像数据
mp2rage_T1_corr：结合B1数据进行发射场B1校正后，由MP2RAGE数据得到的T1图
mp2rage_T1_gdc_brain：经过脑区提取与梯度畸变校正后的MP2RAGE T1图（用于跨中心比较分析）
mp2rage_uni_corr：结合B1数据进行发射场B1校正后的MP2RAGE标准化图像
mp2rage_uni_gdc_brain：经过脑区提取与梯度畸变校正后的MP2RAGE标准化图像（用于跨中心比较分析）
mpm_PD：基于mtflash数据的多参数分析得到的质子密度图（单位：百分比）
mpm_T1：基于mtflash数据的多参数分析得到的T1图（单位：秒）
mpm_T2s：基于mtflash数据的多参数分析得到的T2*图（单位：毫秒）
mtflash3dPD：用于多参数分析的质子密度加权多回波FLASH图像
mtflash3dT1：用于多参数分析的T1加权多回波FLASH图像

并非所有扫描数据都包含完整的上述内容。

如需了解本数据集及分析方法的更多细节，请参阅以下论文：
M. N. Voelker 等，《Traveling Heads 2.0：7特斯拉下定量成像方法的多中心可重复性研究》，《Neuroimage》，2021年2月，文章编号：117910
https://doi.org/10.1016/j.neuroimage.2021.117910
若使用本GUFI数据集，请引用上述论文！

首次上传的数据包（TH2_data_ES_s1.zip）包含受试者1在配置2下首次扫描得到的完整数据集，用于对应论文的审稿流程（本数据包的CEST分析结果在审稿期间进行了优化）。
完整数据集（TH2_alldata.zip）已作为本项目的更新包上传。