Effects of cinnamic acid on the hair growth ability of dermal papilla cells. Effects of cinnamic acid on the hair growth ability of dermal papilla cells

We examined effects of cinnamic acid on the hair growth ability of dermal papilla cells. Treatment with cinnamic acid led to upregulation of G-protein coupled receptor signaling pathway and neuroactive ligand-receptor interaction in human DP cells. Overall design: We annalysed gene expression of human dermal papilla cells with/without 100 μg/mL treatment for 3 days.

本研究探讨了肉桂酸（cinnamic acid）对真皮乳头细胞（dermal papilla cells）毛发生长能力的影响。经肉桂酸处理后，人类真皮乳头细胞（human dermal papilla cells，简称DP细胞）内的G蛋白偶联受体信号通路（G-protein coupled receptor signaling pathway）与神经活性配体-受体相互作用通路均出现上调。整体实验设计：我们对经100 μg/mL肉桂酸处理3天以及未接受处理的人类真皮乳头细胞进行了基因表达分析。