LAPAROSCOPIC TECHNIQUE VERSUS OPEN TECHNIQUE IN SWINES ADRENALECTOMY

Among the main benefits of laparoscopic adrenalectomy (LA) compared to open adrenalectomy (OA) the rapid recovery of patients with decreased length of stay in hospital can be highlighted. The objective of this study was to compare the open adrenalectomy with laparoscopic adrenalectomy in swine. Thirty-two swine were operated. The animals had been divided into four groups (n = 8), one group was submitted to OA and the other to LA, together with its respective control group. Parameters were evaluated regarding operative time, body temperature, hematocrit, postoperative and intraoperative complications and time to deambulation. There was no meaningful difference between operative and deambulation times, even though the latter having been higher in the group submitted to OA. The most frequent intercurrences were in bowel, damage to adrenal vessels and renal hematoma. There were no significant blood losses, and observed hypothermia did not have any clinical impact. Laparoscopy in swine experimental adrenalectomy is a reliable technique that can serve as a reference for the surgical treatment of patients with adrenal diseases with surgical indications in other animal species.

与开放肾上腺切除术（open adrenalectomy, OA）相比，腹腔镜肾上腺切除术（laparoscopic adrenalectomy, LA）的核心优势之一，在于患者术后康复更快、住院时长得以缩短。本研究旨在对比猪模型中开放肾上腺切除术与腹腔镜肾上腺切除术的疗效。本实验共纳入32头实验猪，将其分为4组（每组n=8），其中一组接受开放肾上腺切除术，一组接受腹腔镜肾上腺切除术，另设与之对应的两个对照组。本研究评估了多项指标：手术时长、体温、血细胞比容、术中和术后并发症情况，以及下床活动时间。结果显示，两组手术时长无显著差异；尽管开放肾上腺切除术组的下床活动时间更长，但差异无统计学意义。最常见的并发症为肠道相关事件、肾上腺血管损伤及肾血肿。两组均未出现显著失血量，且观测到的低体温症未产生任何临床影响。综上，在猪实验模型中开展腹腔镜肾上腺切除术是一项可靠的技术，可作为其他具备手术适应证的动物物种中肾上腺疾病患者外科治疗的参考方案。