Distribution of samples, phenotyping and genotyping, and concordance between phenotypic and genotypic tropism.

Distribution of samples per subtype, successful Env PCR amplification, recombinant virus production and sequencing of the V3-loop, and results (concordance and Cohen kappa values) for genotype/phenotype pairs are reported.N: number of samples. G2P: Geno2Pheno(coreceptor). The percentage following G2P indicates the FPR cut-off. Distribution of samples per subtype, successful Env PCR amplification, recombinant virus production and sequencing of the V3-loop, and results (concordance and Cohen kappa values) for genotype/phenotype pairs are reported.*For subtype C, concordance was determined and with webPSSM subtype C SINSI. Concordance with webPSSM X4/R5 was 75% and Cohen kappa values were poor (−0.0989 for full agreement and −0.1365 when detection of X4 strains was considered).本数据集报告了各亚型的样本分布、包膜（Env）聚合酶链反应（PCR）扩增成功率、重组病毒制备与V3环（V3-loop）测序结果，以及基因型/表型对（genotype/phenotype pairs）的分析结果（包括一致性及科恩kappa（Cohen kappa）值）。其中，N代表样本量；G2P为Geno2Pheno（共受体预测工具），其后跟随的百分比表示假阳性率（FPR）截断值。*针对C亚型，本研究采用webPSSM的C亚型SINSI模型进行一致性分析。与webPSSM预测的X4/R5嗜性结果的一致性为75%，科恩kappa值表现较差：完全一致时为-0.0989，仅考虑X4毒株检测时为-0.1365。