Plant essential oil targets TRPV3 for skin renewal and structural mechanism of action

The cryo-EM maps and atomic coordinates of wild-type human TRPV3 in the apo form and ligand-bound states have been deposited in the Electron Microscopy Data Bank and the Protein Data Bank under the accession numbers: EMD-61396, 9JDM for TRPV3Apo, EMD-61407, 9JE5 for TRPV3Citronellal, EMD-61414, 9JEE for TRPV3Citral, EMD-61415, 9JEF for TRPV3Linalool, and EMD-61416, 9JEG for TRPV3Isodihydrolavandulal.野生型人类TRPV3的空载态及各配体结合态的冷冻电镜图与原子坐标，已提交至电子显微镜数据库（Electron Microscopy Data Bank）与蛋白质数据库（Protein Data Bank），对应登录号如下：TRPV3空载态（TRPV3Apo）：EMD-61396、9JDM；香茅醛结合TRPV3（TRPV3Citronellal）：EMD-61407、9JE5；柠檬醛结合TRPV3（TRPV3Citral）：EMD-61414、9JEE；芳樟醇结合TRPV3（TRPV3Linalool）：EMD-61415、9JEF；异二氢薰衣草醛结合TRPV3（TRPV3Isodihydrolavandulal）：EMD-61416、9JEG。