Association between time-weighted average radon exposure<sup>#</sup> and basal cell carcinoma, squamous cell carcinoma and malignant melanoma among 51,445 Diet Cancer Health cohort participants.
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aAdjusted for age (underlying time scale) and sex. bAdjusted for skin reaction to sunlight, degree of freckles, degree of nevi, BMI, school attendance, area-level socio-economic status, leisure time physical activities including sports, cycling, walking and gardening as well as outdoor occupation (farming, mining, quarrying, roofing or asphalt road work) and mean daily hours of bright sunshine at the level of municipality of each residence. Due to exclusion of cohort members with missing value in any covariate, the number of persons is identical in the crude and the adjusted analyses. #Radon exposure was entered as a continuous variable in all models as the time-weighted average at residences from 1 January 1971 until censoring. Association between time-weighted average radon exposure# and basal cell carcinoma, squamous cell carcinoma and malignant melanoma among 51,445 Diet Cancer Health cohort participants.
a 本研究校正了年龄(作为潜在时间尺度)与性别。 b 本研究校正了皮肤日光反应、雀斑严重程度、痣的数目、体重指数(Body Mass Index, BMI)、受教育程度、区域层面社会经济地位、闲暇时间体力活动(涵盖运动、骑行、步行与园艺劳作),以及户外职业(包括农耕、采矿、采石、屋面作业或沥青道路作业),同时校正了各居住所在地级市的日均日照时长。 由于排除了任意协变量存在缺失值的队列成员,粗分析与校正分析的研究人数完全一致。 # 氡暴露在所有模型中以连续变量形式纳入,采用1971年1月1日至截尾时点的居住地址氡暴露时间加权平均值。 本研究探讨了51445名饮食癌症健康队列(Diet Cancer Health cohort)参与者中,时间加权平均氡暴露#与基底细胞癌(basal cell carcinoma)、鳞状细胞癌(squamous cell carcinoma)及恶性黑色素瘤(malignant melanoma)的关联。




