The influence of metformin and diet change on blood glucose regulation and the fecal microbiota of healthy horses

These 16S rRNA amplicon sequencing data were generated using fecal DNA from two groups of horses. Group 1 includes six healthy adult horses that were removed from pasture and changed to an all hay diet, and four of those horses also received oral administration of metformin twice daily for one week. These six horses were also subjected to an oral sugar test at the beginning and end of the one week. Group 2, serving as controls, includes 25 healthy horses remaining on pasture, and sampled at the beginning and end of one week.

本数据集的16S rRNA扩增子测序（16S rRNA amplicon sequencing）数据，由两组马匹的粪便DNA测序获得。第一组包含6匹健康成年马，该组马匹均被移出牧场并更换为全干草日粮，其中4匹还每日两次口服二甲双胍（metformin），持续一周；该6匹马匹在该一周实验周期的起始与结束阶段，均接受了口服糖试验。作为对照的第二组包含25匹仍留在牧场的健康马匹，同样在该一周实验周期的起始与结束阶段完成了采样。