Source data for the diagnostic performance of delayed post gadolinium MRI descriptors across the range of MD clinical classifications

Case-controlled studies documenting the diagnostic performance of delayed post gadolinium MRI descriptors in distinguishing MD ears from asymptomatic ears or ears with other audio-vestibular conditions were identified (MEDLINE, EMBASE, Web of Science, Scopus databases: updated 17/2/2022). The meta-analysis included 66 unique studies and 3073 ears with MD, evaluating 11 MRI descriptors (in columns). The additional sheets pertain to the meta-regression. a)clinical classifications b) control group type (asymptomatic ear contralateral to MD v asymptomatic ears in other subjects v ear with other audio-vestibular condition) c) route of gadolinium administration (IV v IT) d) number of image reviewers (single v multiple observers) e) analysed on an ear basis v patient basis f) depiction of bone signal (intermediate v low) g) low risk of bias (any domain vs none) and high applicability (any vs none) h) study design (prospective v other and consecutive recruitment v other).

本研究检索了旨在明确延迟钆增强磁共振成像（Magnetic Resonance Imaging, MRI）特征在区分梅尼埃病（Meniere’s Disease, MD）患耳与无症状耳或合并其他前庭听觉疾病患耳的诊断性能的病例对照研究，检索数据库涵盖MEDLINE、EMBASE、Web of Science及Scopus，检索更新至2022年2月17日。本次荟萃分析共纳入66项独立研究，涉及3073例梅尼埃病患耳，对11项MRI特征（以列项形式呈现）进行了评估。附加工作表用于荟萃回归分析，具体包括：
a) 临床分类；
b) 对照组类型（梅尼埃病对侧无症状耳、其他受试者的无症状耳、合并其他前庭听觉疾病的患耳）；
c) 钆剂给药途径（静脉给药[IV] vs 鞘内给药[IT]）；
d) 图像阅片者数量（单阅片者 vs 多名阅片者）；
e) 分析维度（以耳为单位 vs 以患者为单位）；
f) 骨信号表现（中等信号 vs 低信号）；
g) 偏倚风险与适用性：偏倚风险低（存在至少一个低偏倚风险领域 vs 无低偏倚风险领域）、适用性高（存在至少一个高适用性领域 vs 无高适用性领域）；
h) 研究设计（前瞻性研究 vs 其他研究；连续性招募 vs 非连续性招募）。