Additional file 2 of Single cell analysis identified IFN signaling activation contributes to the pathogenesis of pediatric steroid-sensitive nephrotic syndrome

Supplementary Material 2. Supplementary Table 1. Inclusion and exclusion criteria of nephrotic syndrome patients. Supplementary Table 2. Detailed information of patients and healthy controls. Supplementary Table 3. Genes highly expressed in each cluster (T cells, B cells, NK cells, monocytes, cDC, pDC, and mast cells) in the STS Pre group. Supplementary Table 4. Genes lowly expressed in each cluster (T cells, B cells, NK cells, monocytes, cDC, pDC, and mast cells) in the STS Pre group. Supplementary Table 5. Enrichment of MSigDB Hallmark gene sets within each major cluster (T cells, B cells, NK cells, monocytes, cDC, pDC, and mast cells) across groups. Supplementary Table 6. Enrichment of MSigDB Hallmark gene sets within each subcluster of T cells, B cells, NK cells, and monocytes across groups. Supplementary Table 7. Interferon-stimulated genes. Supplementary Table 8. RSS scores across groups within each subcluster of T, B, NK, and myeloid cells.

补充材料2。
补充表1. 肾病综合征患者的纳入与排除标准。
补充表2. 患者与健康对照的详细信息。
补充表3. STS Pre组各细胞簇（T细胞、B细胞、NK细胞、单核细胞、经典树突状细胞（conventional dendritic cell, cDC）、浆细胞样树突状细胞（plasmacytoid dendritic cell, pDC）及肥大细胞）的高表达基因。
补充表4. STS Pre组各细胞簇（T细胞、B细胞、NK细胞、单核细胞、cDC、pDC及肥大细胞）的低表达基因。
补充表5. 跨各组各主要细胞簇（T细胞、B细胞、NK细胞、单核细胞、cDC、pDC及肥大细胞）中MSigDB特征基因集的富集分析结果。
补充表6. 跨各组T细胞、B细胞、NK细胞及单核细胞各亚簇中MSigDB特征基因集的富集分析结果。
补充表7. 干扰素刺激基因。
补充表8. T、B、NK及髓系细胞各亚簇内跨各组的RSS评分。