Crystal Structure of S. pneumoniae Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor

Protein Data Bank Japan2023-11-01 更新2026-03-21 收录

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Crystal Structure of S. pneumoniae Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID, CALCIUM ION, ... Authors: Saito, J, Yamada, M, Watanabe, T, Takeuchi, Y. Deposit date: 2007-08-01 Release date: 2008-04-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor. Protein Sci., 17, 2008

肺炎链球菌（Streptococcus pneumoniae）烯酰-酰基载体蛋白还原酶（enoyl-acyl carrier protein reductase, FabK）与抑制剂复合物的晶体结构。数据集描述：(4S)-2-甲基-2,4-戊二醇、2-(4-(2-((3-(5-(吡啶-2-基硫代)噻唑-2-基)脲基)甲基)-1H-咪唑-4-基)苯氧基)乙酸、钙离子…… 作者：Saito J、Yamada M、Watanabe T、Takeuchi Y。提交日期：2007-08-01，发布日期：2008-04-01，最后修改日期：2023-11-01。实验方法：X射线衍射（分辨率2.3埃）。引用文献：《肺炎链球菌烯酰-酰基载体蛋白还原酶（FabK）的晶体结构揭示了抑制剂的结合模式》，《Protein Sci.》，第17卷，2008年

创建时间：

2007-08-01