Histological analysis of the effect of global HPC on retinal ischemic damage.

Total retinal and retinal layer thicknesses (in µm) in non-ischemic or ischemic eyes without or with global HPC. Retinal ischemia induced a significant decrease in total retinal, ONL, INL and IPL thickness, and in GCL Brn3a(+) cell number. The alterations in total retinal, INL, and IPL (but not ONL) thickness, and in retinal ganglion cell number were partially prevented by global HPC, which showed no effects in non-ischemic eyes on these parameters. Data are mean ± SEM (n = 5 eyes per group).*P**PapbpPS, photoreceptor outer and inner segment; OPL, outer plexiform layer; ONL, outer nuclear layer; IPL, inner plexiform layer; INL, inner nuclear layer.本数据集收录了伴或不伴整体缺氧预处理（global HPC）的非缺血性与缺血性眼部的视网膜总厚度及视网膜各层厚度（单位：μm）。视网膜缺血可显著降低视网膜总厚度、外核层（outer nuclear layer, ONL）、内核层（inner nuclear layer, INL）以及内丛状层（inner plexiform layer, IPL）的厚度，同时降低Brn3a阳性视网膜神经节细胞数量。整体缺氧预处理可部分逆转视网膜总厚度、内核层（INL）、内丛状层（IPL）（而非外核层ONL）的厚度异常，以及视网膜神经节细胞数量的改变；且该预处理对非缺血性眼部的上述参数无显著影响。数据以平均值±标准误（standard error of the mean, SEM）表示，每组n=5只眼部。*P*注：光感受器内外节（photoreceptor outer and inner segment, PapbpPS）；外丛状层（outer plexiform layer, OPL）；外核层（outer nuclear layer, ONL）；内丛状层（inner plexiform layer, IPL）；内核层（inner nuclear layer, INL）。