Error-corrected Duplex Sequencing of MutaMouse male germ cells exposed to Benzo[b]fluoranthene

The goal of this study was to characterize the mutagenic effects of Benzo[b]fluoranthene in the germ cells of MutaMouse males using Duplex Sequencing. Duplex Sequencing was applied to obtain mutation frequency and information on mutation spectra.本研究旨在采用双链测序（Duplex Sequencing）技术，表征苯并[b]荧蒽对雄性MutaMouse小鼠生殖细胞的诱变效应。研究通过该技术获取了突变频率与突变谱相关信息。