Gene expression pattern change upon H2O2 treatment in P. pastoris

Here we performed RNA-seq to examine gene expression difference in regular culture and H2O2 treated cells. Two strains were used here: GS115 (wild-type) and GS115-delta PAS_chr1-4_0287/PAS_chr1-1_0102/PAS_chr2-2_0494 (H3K36me3 deficient strain).

本研究通过RNA测序（RNA-seq）技术，分析常规培养与H₂O₂处理的细胞之间的基因表达差异。本研究使用了两种菌株：GS115（野生型）以及GS115-ΔPAS_chr1-4_0287/PAS_chr1-1_0102/PAS_chr2-2_0494（组蛋白H3赖氨酸36三甲基化（H3K36me3）缺陷型菌株）。