One anastomosis gastric bypass (OAGB): Scoping review

This release archives the complete reproducibility package for the peer-reviewed scoping review: Ortíz-Gómez JE, González-Barajas AI, Guevara-Díaz JA, Mancilla-Galindo J, Kammar-García A, Guerrero-Gutierrez MA. One anastomosis gastric bypass (OAGB): a scoping review. BMC Surgery. 2025;25(1):471. https://doi.org/10.1186/s12893-025-03215-x The article is Open Access under a CC BY 4.0 license. This archive (code, data, and documentation) is released under the MIT License. About the study This scoping review synthesises evidence from 67 studies (out of 3,791 records screened) on One Anastomosis Gastric Bypass (OAGB), also known as mini-gastric bypass (MGB), across four clinical domains: percentage excess weight loss (%EWL), remission of metabolic and cardiovascular conditions, postoperative complications, and incidence of gastroesophageal reflux disease (GERD). Key findings: OAGB showed higher or comparable %EWL versus Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and SADI-S, particularly in short- and mid-term follow-up. Type 2 diabetes remission ranged from 76.8% to 100%, with meaningful improvements in hypertension, dyslipidemia, and obstructive sleep apnea. GERD and bile reflux remain the main long-term concerns; reported de novo GERD rates ranged from 6% to 57%, and the YOMEGA randomised trial reported 41% in OAGB versus 18% in RYGB. Longer biliopancreatic limbs enhanced weight loss but increased nutritional risk. Substantial heterogeneity in how outcomes (especially %EWL and "ideal weight") were defined across studies limits meta-analytic comparability and motivates a call for standardised reporting. Methodologically, the review followed PRISMA-ScR, used the ASReview active-learning tool for AI-assisted record screening, and the ASySD tool for deduplication. Contents of this archive R/ — Quarto (.qmd) source files documenting the literature search, deduplication, and ASReview record handling. asreview/ — exported ASReview project files, importable into ASReview LAB to inspect screening decisions and reproduce the active-learning workflow. docs/reports/ — rendered PDF and DOCX reports of each analysis step. docs/rob/ — full Cochrane RoB 2.0 assessment for the included randomised controlled trials. data/ — raw and processed search outputs. results/ — figures and tables generated from the analysis. Reuse scenarios Re-running or extending the literature search with updated dates. Importing the ASReview project to audit screening decisions or to use as prior knowledge for related evidence syntheses on bariatric surgery. Adapting the search strategy or the ASReview workflow as a template for other scoping or systematic reviews. Citing the methodological approach (PRISMA-ScR + ASReview active-learning screening + Cochrane RoB 2.0) in the methods sections of future evidence-synthesis work. How to cite If you reuse any part of this archive, please cite both the published article (preferred) and this Zenodo record: Article: Ortíz-Gómez JE, González-Barajas AI, Guevara-Díaz JA, Mancilla-Galindo J, Kammar-García A, Guerrero-Gutierrez MA. One anastomosis gastric bypass (OAGB): a scoping review. BMC Surgery. 2025;25(1):471. doi:10.1186/s12893-025-03215-x Related resources GitHub repository (live version): https://github.com/javimangal/OAGB-review Published article (Open Access): https://doi.org/10.1186/s12893-025-03215-x Software and reproducibility Analyses were conducted in R version 4.5.0 with RStudio 2025.05.0. Screening used ASReview LAB v.2.0.2. Deduplication used ASySD. Risk-of-bias assessment used the Cochrane RoB 2.0 Excel implementation. Keywords bariatric surgery; metabolic and bariatric surgery; one anastomosis gastric bypass; OAGB; mini-gastric bypass; MGB; Roux-en-Y gastric bypass; RYGB; sleeve gastrectomy; SADI-S; obesity; obesity management; type 2 diabetes remission; gastroesophageal reflux disease; GERD; bile reflux; biliopancreatic limb; nutritional deficiencies; scoping review; evidence synthesis; PRISMA-ScR; ASReview; active learning; AI-assisted screening; Cochrane RoB 2.0本存档包为经同行评议的范围综述（scoping review）提供完整的可复现研究包： Ortíz-Gómez JE, González-Barajas AI, Guevara-Díaz JA, Mancilla-Galindo J, Kammar-García A, Guerrero-Gutierrez MA. 单吻合口胃旁路术（One Anastomosis Gastric Bypass，OAGB）：一项范围综述. BMC Surgery. 2025;25(1):471. https://doi.org/10.1186/s12893-025-03215-x 本文采用CC BY 4.0许可协议开放获取。本存档包（含代码、数据与文档）采用MIT许可协议发布。 ## 研究概述 本范围综述对单吻合口胃旁路术（One Anastomosis Gastric Bypass，OAGB，又称迷你胃旁路术mini-gastric bypass，MGB）的相关证据进行了综合分析，共纳入经3791条文献记录筛选后得到的67项研究，涵盖四大临床领域：多余体重丢失百分比（%EWL）、代谢与心血管疾病缓解情况、术后并发症以及胃食管反流病（gastroesophageal reflux disease，GERD）发病率。 ### 主要研究结果 1. 与Roux-en-Y胃旁路术（Roux-en-Y gastric bypass，RYGB）、袖状胃切除术（sleeve gastrectomy，SG）及SADI-S相比，单吻合口胃旁路术的多余体重丢失百分比更高或相当，尤其在短期与中期随访中。 2. 2型糖尿病缓解率介于76.8%至100%之间，高血压、血脂异常与阻塞性睡眠呼吸暂停均得到显著改善。 3. 胃食管反流病与胆汁反流仍是主要的长期关注点；新发胃食管反流病报告率介于6%至57%之间，YOMEGA随机对照试验显示，单吻合口胃旁路术组新发GERD率为41%，而Roux-en-Y胃旁路术组为18%。 4. 更长的胆胰袢可提升减重效果，但会增加营养风险。 5. 不同研究对结局指标（尤其是多余体重丢失百分比与“理想体重”）的定义存在显著异质性，这限制了荟萃分析的可比性，也呼吁建立标准化的报告规范。 ### 方法学说明 本范围综述遵循PRISMA-ScR规范，采用ASReview主动学习工具开展AI辅助文献筛选，并使用ASySD工具完成文献去重工作。 ## 存档包内容 - `R/`：Quarto（.qmd）源文件，用于记录文献检索、去重及ASReview文献处理流程。 - `asreview/`：导出的ASReview项目文件，可导入ASReview LAB以审查筛选决策并复现主动学习工作流。 - `docs/reports/`：各分析步骤生成的可渲染PDF与DOCX格式报告。 - `docs/rob/`：纳入的随机对照试验的完整Cochrane RoB 2.0偏倚风险评估报告。 - `data/`：原始与经过预处理的文献检索结果。 - `results/`：分析过程生成的图表与表格。 ## 复用场景 1. 重新运行或扩展文献检索流程，更新检索日期。 2. 导入ASReview项目文件以审查筛选决策，或作为减重手术相关证据合成工作的先验知识。 3. 调整检索策略或ASReview工作流，作为其他范围综述或系统综述的模板。 4. 在未来证据合成类研究的方法学部分，引用本研究采用的方法学框架（PRISMA-ScR + ASReview主动学习筛选 + Cochrane RoB 2.0）。 ## 引用方式 若复用本存档包的任何内容，请同时引用已发表论文（优先选择）与本Zenodo存档： > 论文：Ortíz-Gómez JE, González-Barajas AI, Guevara-Díaz JA, Mancilla-Galindo J, Kammar-García A, Guerrero-Gutierrez MA. 单吻合口胃旁路术（OAGB）：一项范围综述. BMC Surgery. 2025;25(1):471. doi:10.1186/s12893-025-03215-x ## 相关资源 - GitHub仓库（在线版本）：https://github.com/javimangal/OAGB-review - 已发表论文（开放获取）：https://doi.org/10.1186/s12893-025-03215-x ## 软件与可复现性 本分析基于R 4.5.0版本与RStudio 2025.05.0完成。文献筛选使用ASReview LAB v2.0.2，文献去重使用ASySD工具，偏倚风险评估采用Cochrane RoB 2.0的Excel实现版本。 ## 关键词 减重代谢手术；代谢与减重手术；单吻合口胃旁路术；OAGB；迷你胃旁路术；MGB；Roux-en-Y胃旁路术；RYGB；袖状胃切除术；SADI-S；肥胖；肥胖管理；2型糖尿病缓解；胃食管反流病；GERD；胆汁反流；胆胰袢；营养缺乏；范围综述；证据合成；PRISMA-ScR；ASReview；主动学习；AI辅助筛选；Cochrane RoB 2.0