Lycopene in The BioCycle Study

Lycopene
Study Description
The BioCycle Study is a prospective cohort study completed at the University at Buffalo and offers a unique and comprehensive assessment of menstrual cycle function. The primary goal of the BioCycle Study was to better understand the intricate relationship between reproductive hormone levels and oxidative stress during the menstrual cycle. Multiple markers of oxidative stress, reproductive hormones, inflammation, and metabolic biomarkers were measured in a cohort of 259 women of reproductive age over the course of two menstrual cycles. Fertility monitors were utilized to time the subjects' visits to ensure appropriate timing of biospecimen collection. Additional information regarding diet, lifestyle, and physical measurements was obtained throughout the study via standardized questionnaires, anthropometric assessments, and daily diaries. Participants were highly adherent to the study protocol, with 94% of all women completing seven or eight visits per cycle. Regularly menstruating premenopausal female volunteers aged 18–44 years from the western New York state region.

番茄红素（Lycopene）
研究描述
BioCycle研究（BioCycle Study）是由布法罗大学开展完成的一项前瞻性队列研究(prospective cohort study)，可对月经周期功能开展独具特色且全面的评估。本研究的核心目标为深入阐明月经周期内生殖激素水平与氧化应激(oxidative stress)之间的复杂关联。研究共纳入259名育龄女性，在两个完整月经周期内对其氧化应激、生殖激素、炎症及代谢相关生物标志物进行了多维度检测。研究采用生育监测仪(Fertility monitors)规划受试者的随访时间，以确保生物样本采集的时机精准恰当。研究期间，还通过标准化问卷、人体测量学评估以及每日日记，收集了受试者的饮食、生活方式及身体测量指标相关的补充信息。受试者对研究方案的依从性极佳，94%的女性可在每个月经周期内完成7至8次随访。本研究的招募对象为来自纽约州西部地区、年龄18至44岁、月经规律的绝经前女性志愿者。