Probability of the spectrum of rpoB mutations in the INH-resistant mutant and the wildtype parent being identical.

The probability of hypothesis h0b (the spectrum of rpoB-mutations of the INH-resistant mutant is not different than that of the wildtype parent) determined by X2 for all INH-resistant strains for both methods. For all of the tested strains the statistical power of the X2 test was reduced due to one or more mutations occurring less than five times. NA: not available, mutants were not obtained for these strains.
*: since both 2001-1669 and 2001-1670 are resistant to INH (via katG-S315T), the spectrum was compared to the only susceptible LAM strain, 9900098. Bold: pa<0.05, therefore hypothesis is rejected.

针对所有耐异烟肼（isoniazid，简称INH）菌株，采用两种方法通过卡方（X²）检验计算原假设h0b的概率——该假设内容为：耐异烟肼突变株的rpoB基因突变谱与野生型亲本株无差异。对于所有受试菌株，由于存在1个或多个出现次数少于5次的突变，卡方检验的统计功效有所降低。NA：数据不可用，此类菌株未获得突变株。
*：因菌株2001-1669与2001-1670均通过katG-S315T突变产生异烟肼耐药性，故将其突变谱与唯一的易感LAM菌株9900098进行比对。加粗标注：pa<0.05，因此拒绝原假设。