Modeling Exosome Complexes From Cross-Link Ms Data

This repository contains the modeling scripts, the ensemble of models, and the results of the analysis for the modeling of the <em>S.cerevisiae</em> exosome complex (named exo10, comprising of Rrp40, Rrp4, Csl4, Rrp45, Rrp46, Rrp42, Rrp43, Mtr3, Ski6 and Rrp44), in presence of Ski7 (exo10+Ski7 below) or Rrp6 (exo10+Rrp6 below) proteins. The modeling is performed based on cross-link Mass-Spectrometry data, crystallographic structures, and comparative models.本代码仓库收录了酿酒酵母（S. cerevisiae）外切酶体复合物的建模脚本、集成模型集及相关分析结果。该复合物被命名为exo10，由Rrp40、Rrp4、Csl4、Rrp45、Rrp46、Rrp42、Rrp43、Mtr3、Ski6与Rrp44组成，且分别在添加Ski7（下文简称exo10+Ski7）或Rrp6（下文简称exo10+Rrp6）蛋白的条件下完成建模。本次建模基于交联质谱（cross-link Mass-Spectrometry）数据、晶体结构及比较建模模型开展。