Claim Verification: "Co-occurrence of Lewy pathology and ADNC is common (≥30% of AD cases have LP; ≥50% of DLB cases have ADNC)" — Proved

Automated fact-verification of the claim: "Co-occurrence of Lewy pathology and ADNC is common (≥30% of AD cases have LP; ≥50% of DLB cases have ADNC)" Verdict: PROVED Key Findings SC1 confirmed: At least 3 independent sources report that ≥30% of Alzheimer's disease (AD) cases have co-occurring Lewy pathology (LP). The NACC database (n=2,742) reports 38% co-occurrence of Lewy body disease (LBD) in participants with Alzheimer's disease neuropathologic change (ADNC) (B1). Lewy body pathology is described as the most common co-existing pathology in AD cases up to age 80 (B3). SC2 confirmed: At least 4 independent sources confirm that ≥50% of dementia with Lewy bodies (DLB) cases have co-occurring ADNC. Toledo et al. 2023 explicitly states AD co-pathology "is present in more than 50% of DLB individuals" (B5). The Mayo Clinic brain bank reports 59% (215/363) comorbid AD in Lewy body dementia (B7). Both sub-claims hold: the compound claim is PROVED with all 8 citations verified. Files proof.py — Re-runnable Python verification script proof.md — Structured proof report proof_audit.md — Full verification audit trail proof_narrative.md — Plain-language summary proof.json — Machine-readable structured data Generated by Proof Engine v1.13.0.针对以下声明的自动化事实核查：“路易体病理（Lewy pathology, LP）与阿尔茨海默病神经病理改变（Alzheimer's disease neuropathologic change, ADNC）共现情况较为常见——≥30%的阿尔茨海默病（Alzheimer's disease, AD）患者存在路易体病理；≥50%的路易体痴呆（dementia with Lewy bodies, DLB）患者存在阿尔茨海默病神经病理改变”。 核查结论：已证实（PROVED） 关键发现 SC1已证实：至少3项独立来源指出，≥30%的阿尔茨海默病（AD）患者存在共现路易体病理（LP）。美国阿尔茨海默病协调中心（National Alzheimer Coordinating Center, NACC）数据库（样本量n=2742）显示，合并阿尔茨海默病神经病理改变（ADNC）的受试者中，路易体病（Lewy body disease, LBD）共现率为38%（B1）。研究表明，在80岁及以下的AD患者中，路易体病理是最常见的共发病理类型（B3）。 SC2已证实：至少4项独立来源证实，≥50%的路易体痴呆（DLB）患者存在共现阿尔茨海默病神经病理改变（ADNC）。Toledo等人2023年的研究明确指出，阿尔茨海默病共病理“在超过50%的DLB患者中存在”（B5）。梅奥诊所（Mayo Clinic）脑库报告显示，路易体痴呆患者中合并阿尔茨海默病的比例为59%（215/363）（B7）。 两项子主张均成立：结合全部8项经验证的引用文献，本复合声明已被证实。 相关文件 proof.py — 可重复运行的Python验证脚本 proof.md — 结构化验证报告 proof_audit.md — 完整验证审核追踪记录 proof_narrative.md — 通俗语言总结 proof.json — 机器可读的结构化数据 本报告由Proof Engine v1.13.0生成。