scRNA-Seq of MDMX C462A and wildtype mice treated with acetaminophen

We report the application of scRNA sequencing technology for profiling of acetaminophen response in MDMXC462A mice. These data were used to evaluate differential gene expression and changes in cell composition using canonical markers for mouse liver cells. Overall design: Examination of 2 different histone modifications in Neural progenitor cells.

本研究报道了单细胞RNA测序（scRNA sequencing）技术在MDMXC462A小鼠对乙酰氨基酚（acetaminophen）应答谱分析中的应用。该数据集借助小鼠肝细胞的经典标志物，用于评估差异基因表达水平与细胞组成变化。总体实验设计：对神经前体细胞（Neural progenitor cells）中的两种不同组蛋白修饰（histone modifications）进行检测。