Saccharomyces cerevisiae strain:FY4 (S288c) Transcriptome or Gene expression

Cell growth is regulated in response to resource availability including the abundance, and molecular form, of essential nutrients. In the model eukaryotic cell, Saccharomyces cerevisiae (budding yeast), the molecular form of environmental nitrogen impacts both cell growth rate and mRNA expression. Disentangling causal relationships between nitrogen availability, cell growth rate and differential gene expression poses a considerable challenge. We studied the effect of environmental nitrogen on differential gene expression.

细胞生长会响应资源可获得性（包括必需营养素的丰度与分子形式）而受到调控。在模式真核细胞酿酒酵母（Saccharomyces cerevisiae，又称出芽酵母）中，环境氮的分子形式会同时影响细胞生长速率与信使RNA（mRNA）的表达。厘清氮可获得性、细胞生长速率与差异基因表达之间的因果关系，是一项颇具挑战性的任务。本研究针对环境氮对差异基因表达的影响展开了探究。